
Polynucleotide (PDRN) Injection
DNA-repair injections for deep skin regeneration
Polynucleotide (PDRN) injections use purified DNA fragments to stimulate tissue repair, collagen synthesis and deep hydration. Injected into the dermis, they produce visible improvements in skin quality, firmness and radiance over a course of sessions.
PDRN activates cellular repair pathways and promotes growth factor production, making it particularly effective for skin damaged by sun exposure, ageing, acne scarring or dryness. It is often combined with hyaluronic acid skin boosters or mesotherapy for enhanced results.
Key Benefits
- Stimulates DNA repair and collagen synthesis in ageing skin
- Deep hydration and barrier restoration
- Effective for skin damaged by sun, acne or ageing
- Combinable with skin boosters for amplified results
Is This Treatment Right For You?
- Patients with sun-damaged, dehydrated or dull skin
- Those with acne scars seeking regenerative repair
- Anyone wanting a science-backed skin quality treatment
What to Expect
Skin Assessment
Skin quality, damage and hydration are evaluated.
Treatment Planning
PDRN product and injection technique are selected.
Intradermal Injections
PDRN is injected across the treatment area using fine needles or a mesotherapy gun.
Follow-Up
Review at 4 weeks; a course of 3–4 sessions is typically recommended.
Recovery & Aftercare
Small injection papules settle within 24 hours; mild redness resolves in 1–2 days.
Frequently Asked Questions
Are polynucleotide injections the same as PRP?
No — PDRN uses purified DNA fragments, while PRP uses the patient's own platelets. Both stimulate regeneration but through different mechanisms.
Is it painful?
Topical numbing cream is applied before treatment, and the fine needles used make the procedure well tolerated.
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Learn MoreReady to Book Your Polynucleotide (PDRN) Injection Consultation?
Speak to a specialist and get an honest, personalised recommendation.